Mediket Versi Cleansing Gel for Skin and Scalp 200ml Tinea Versicolor

Product Information

Read all of this leaflet carefully before you or your child start taking this medicine because it contains important information for you. There is a small increase in risk of heart problems when methylphenidate is taken during the first three months of pregnancy. One in 53 babies whose mums took methylphenidate experienced heart problems compared to one in 79 whose mums didn’t take methylphenidate. The safety and efficacy of long-term use of methylphenidate has not been systematically evaluated in controlled trials. Methylphenidate treatment should not and need not, be indefinite. Methylphenidate treatment can usually be discontinued during or after puberty, when used in children with ADHD. The physician who elects to use methylphenidate for extended periods (over 12 months) should periodically re-evaluate the long-term usefulness of the medicinal product for the individual patient with trial periods off medication to assess the patient's functioning without pharmacotherapy. It is recommended that methylphenidate is de-challenged at least once yearly to assess the patient's condition (for children preferably during times of school holidays). Improvement may be sustained when the medicinal product is either temporarily or permanently discontinued. If you forget doses often, it may help to set an alarm to remind you. You could also ask your pharmacist for advice on other ways to help you remember to take your medicine. What if I take too much? Each modified-release capsule hard contains 30 mg methylphenidate hydrochloride, equivalent to 25.95 mg methylphenidate.

Medikinet XL consists of an immediate-release component (50% of the dose) and a modified-release component (50% of the dose). Hence Medikinet XL 10 mg yields an immediate-release dose of 5 mg and an extended-release dose of 5 mg methylphenidate hydrochloride. The extended-release portion of each dose is designed to maintain a treatment response through the afternoon without the need for a midday dose. It is designed to deliver therapeutic plasma levels for a period of approximately 8 hours, which is consistent with the school day rather than the whole day (see section 5.2). For example, 20 mg of Medikinet XL is intended to take the place of 10 mg at breakfast and 10 mg at lunchtime of immediate-release methylphenidate hydrochloride. has very high blood pressure or narrowing of the blood vessels, which can cause pain in the arms and legs Convulsions, Choreoathetoid movements, Reversible ischaemic neurological deficit, Neuroleptic malignant syndrome (NMS; Reports were poorly documented, and, in most cases, patients were also receiving other medicinal products, so the role of methylphenidate is unclear). If the effect of the medicinal product wears off too early in the evening, disturbed behaviour may recur.Any treatment with methylphenidate requires individual dose titration against efficacy and tolerability because individual response may vary substantially. Initiation of treatment in adults who are new to Medikinet XL therefore requires careful dose titration. Dose titration should be started at the lowest possible dose.

After approval for the treatment of ADHD in children Medikinet XL has been investigated in two randomised, double-blind, placebo-controlled clinical studies on adult patients. 363 patients were investigated in the EMMA study (1) during a treatment period lasting 24 weeks. In the QUMEA study (2) 162 patients were treated for a total of 20 weeks. After the 8-week-double-blind-phase of this, all patients were treated in the open phase for further 12 weeks with Medikinet XL. The main target parameter in both studies was WRI score reduction (Wender-Reimherr-Interview = WRAADS). The measurement time point was week 24 (study 1) or week 8 (study 2). The aim of individual titration should be to find the lowest daily dose that achieves satisfactory symptom control. Please look at the leaflet inside your medicine box, or ask a doctor or pharmacist, if you want to know whether you are getting a side effect from your medicine. Methylphenidate treatment is not indicated in all patients with ADHD and the decision to use the medicinal product must be based on a very thorough assessment of the severity and chronicity of the patient's symptoms. When treatment of children is considered, assessment of the severity and chronicity of the child's symptoms should be related to the child's age (6 - 18 years).The participants receive either cognitive behavioral group psychotherapy or individual clinical management with the offer for counseling in individual sessions in addition to daily doses of placebo or Medikinet XL. Treatment was conducted for 52 weeks. If you're taking the brand called Equasym XL, take it before breakfast. If you are taking Medikinet XL, take it with or after breakfast. Other side effects include the following, if they get serious, please tell your doctor or pharmacist:

during treatment with non-selective, irreversible monoamine oxidase (MAO) inhibitors, or within a minimum of 14 days of discontinuing those medicinal products, due to risk of hypertensive crisis (see section 4.5) The short- and long-term clinical consequences of these cardiovascular effects in children and adolescents are not known, but the possibility of clinical complications cannot be excluded as a result of the effects observed in the clinical trial data. Caution is indicated in treating patients whose underlying medical conditions might be compromised by increases in blood pressure or heart rate . See section 4.3 for conditions in which methylphenidate treatment is contraindicated. Suicidal attempt (including completed suicide) *, Transient depressed mood*, Abnormal thinking, Apathy #, Repetitive behaviours, Over-focussing There are other side effects that you can get when taking this medicine – we have only included the most common ones here. Studies in animals have only shown evidence of reproductive toxicity at maternally toxic doses (see section 5.3).Each modified-release capsule, hard contains 40 mg methylphenidate hydrochloride equivalent to 34.60 mg methylphenidate. Blood pressure and pulse should be recorded on a centile chart at each adjustment of dose and then at least every 6 months. The usual starting dose for adults is 10mg, taken once in the morning. Your doctor may increase the dose gradually (usually weekly) until they find the dose that works best for you. Dose for slow release tablets