Depresanum 30 Tablets

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Serotonin antagonists and reuptake inhibitors (e.g., etoperidone, hydroxynefazodone, lubazodone, mepiprazole, nefazodone, triazoledione, trazodone) Ergolines (e.g., amesergide, LY-53857, LY-215,840, mesulergine, metergoline, methysergide, sergolexole)

Tricyclic antidepressants (e.g., amitriptyline, butriptyline, clomipramine, desipramine, dosulepin (dothiepin), doxepin, imipramine, iprindole, lofepramine, nortriptyline, protriptyline, trimipramine) Desipramine Hydrochloride". Martindale: The Complete Drug Reference. London, UK: Pharmaceutical Press. 13 December 2013 . Retrieved 17 July 2014.Desipramine was developed by Geigy. [49] It first appeared in the literature in 1959 and was patented in 1962. [49] The drug was first introduced for the treatment of depression in 1963 or 1964. [49] [50] Society and culture [ edit ] Generic names [ edit ] Shen Y, Monsma FJ, Metcalf MA, Jose PA, Hamblin MW, Sibley DR (August 1993). "Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype". The Journal of Biological Chemistry. 268 (24): 18200–18204. doi: 10.1016/S0021-9258(17)46830-X. PMID 8394362. a b Wander TJ, Nelson A, Okazaki H, Richelson E (December 1986). "Antagonism by antidepressants of serotonin S1 and S2 receptors of normal human brain in vitro". European Journal of Pharmacology. 132 (2–3): 115–121. doi: 10.1016/0014-2999(86)90596-0. PMID 3816971.

a b Toll L, Berzetei-Gurske IP, Polgar WE, Brandt SR, Adapa ID, Rodriguez L, etal. (March 1998). "Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications". NIDA Research Monograph. 178: 440–466. PMID 9686407.a b c Martin A, Volkmar FR, Lewis M (2007). Lewis's Child and Adolescent Psychiatry: A Comprehensive Textbook. Lippincott Williams & Wilkins. pp.764–. ISBN 978-0-7817-6214-4. The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using desipramine, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems ( heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death). Rakel RE (May 2007). Textbook of Family Medicine E-Book. Elsevier Health Sciences. pp.313–. ISBN 978-1-4377-2190-4.

Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp.94–. ISBN 978-94-011-4439-1. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Janowsky DS, Byerley B (October 1984). "Desipramine: an overview". The Journal of Clinical Psychiatry. 45 (10 Pt 2): 3–9. PMID 6384207. Read the Medication Guide provided by your pharmacist before you start taking desipramine and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Older adults may be more sensitive to the side effects of this drug, especially dizziness (more likely when standing up), drowsiness, constipation, trouble urinating, mental/mood changes (such as confusion, agitation) and heart effects such as QT prolongation (see above). Dizziness, drowsiness, and confusion can increase the risk of falling.

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Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Desipramine is a very potent and relatively selective norepinephrine reuptake inhibitor (NRI), which is thought to enhance noradrenergic neurotransmission. [33] [34] Based on one study, it has the highest affinity for the norepinephrine transporter (NET) of any other TCA, [16] and is said to be the most noradrenergic [35] and the most selective for the NET of the TCAs. [33] The observed effectiveness of desipramine in the treatment of ADHD was the basis for the development of the selective NRI atomoxetine and its use in ADHD. [33] Tricyclic antidepressants (e.g., amitriptyline ( +perphenazine), amitriptylinoxide, butriptyline, cidoxepin, clomipramine, desipramine, desmethyldesipramine, dibenzepin, dosulepin (dothiepin), doxepin, imipramine, lofepramine, nitroxazepine, northiaden (desmethyldosulepin), nortriptyline, protriptyline, quinupramine, trimipramine) Agonists: 25H/NB series (e.g., 25I-NBF, 25I-NBMD, 25I-NBOH, 25I-NBOMe, 25B-NBOMe, 25C-NBOMe, 25TFM-NBOMe, 2CBCB-NBOMe, 25CN-NBOH, 2CBFly-NBOMe)

Tetracyclic antidepressants (e.g., amoxapine, aptazapine, esmirtazapine, maprotiline, mianserin, mirtazapine) Desipramine is the generic name of the drug and its INN Tooltip International Nonproprietary Name and BAN Tooltip British Approved Name, while desipramine hydrochloride is its USAN Tooltip United States Adopted Name, USP Tooltip United States Pharmacopeia, BAN Tooltip British Approved Name, and JAN Tooltip Japanese Accepted Name. [1] [2] [51] [3] Its generic name in French and its DCF Tooltip Dénomination Commune Française are désipramine, in Spanish and Italian and its DCIT Tooltip Denominazione Comune Italiana are desipramina, in German is desipramin, and in Latin is desipraminum. [2] [3] Brand names [ edit ] Typical antipsychotics (e.g., chlorpromazine, chlorprothixene, cyamemazine (cyamepromazine), loxapine, mesoridazine, thioridazine) a b c Andersen J, Kristensen AS, Bang-Andersen B, Strømgaard K (July 2009). "Recent advances in the understanding of the interaction of antidepressant drugs with serotonin and norepinephrine transporters". Chemical Communications (25): 3677–3692. doi: 10.1039/b903035m. PMID 19557250. Gold MS, Carman JS, Lydiard RB (2 July 1984). Advances in Psychopharmacology. CRC Press. pp.98–. ISBN 978-0-8493-5680-3.

Dart RC (2004). Medical Toxicology. Lippincott Williams & Wilkins. pp.836–. ISBN 978-0-7817-2845-4.